Plasma Exchange in Pediatric Autoimmune Encephalitis

Sex: All

Ages: 1 Month – 18 Years

Healthy volunteers: No

Phase: NA

Enrollment: 22

Sponsor: Menoufia University

Location: Menoufia university hospital, Pediatric intensive care unit Shibīn al Kawm Menoufia Governorate

Summary

The aim of the study will be to compare the efficacy of daily plasma exchange (PLEX) versus alternate-day PLEX in achieving a favorable functional outcome in children with autoimmune encephalitis. The study population will be divided into two groups, the first group will perform PLEX on consecutive days and the second one will perform it every other day. Then, A Favorable functional outcome measure defined as modified Rankin Scale (mRS) score ≤ 2. The mRS will be assessed by a blinded assessor at the end of the sessions to determine which method has superior efficacy in treatment of autoimmune encephalitis.

Eligibility Criteria

Inclusion Criteria: * Childern diagnosed as autoimmune encephalitis according to Cellucci et al., 2020; acute/subacute onset (\2 despite correction, platelets \

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07707739). StuddyBuddy aggregates publicly available trial information.