LASER VERSUS CRYSTALLIZED PHENOL IN PILONIDAL SINUS DISEASE

This single-center prospective randomized parallel-group trial compares laser ablation and crystallized phenol application in adults with primary uncomplicated sacrococcygeal pilonidal sinus disease. The primary objective is to compare postoperative day 1 pain intensity between the two treatment methods. Secondary objectives include complete epithelialization by day 30, time to complete epithelialization, postoperative day 7 pain, duration of analgesic use, time to return to daily activities and work, early local complications, and 6-month recurrence.

Inclusion Criteria: * Age 18 years or older * Diagnosis of primary chronic sacrococcygeal pilonidal sinus disease * Uncomplicated disease * Suitability for minimally invasive treatment * Provision of written informed consent Exclusion Criteria: * Acute pilonidal abscess * History of pilonidal abscess drainage * Previous surgical or interventional treatment for pilonidal sinus disease * Recurrent pilonidal disease * Complex pilonidal disease or marked lateral extension * Immunosuppression, chronic steroid use, or systemic conditions that may significantly impair wound healing * Inability to attend regular follow-up * Refusal to participate in the study