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Completed
NCT07700394
Different Treatment Options For Mature Teeth With Apical Periodontitis
Conditions: Apical Periodontitis
Sex: All
Ages: 18 Years – 30 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 30
Sponsor: Sara Tariq Elemam
Location: Faculty of dentistry ain shams university Cairo
Summary
A randomized control trial which aim to compare the healing potential for the following treatment options for mature teeth with apical periodontitis:
Group I: Conventional root canal treatment (CRT) Group II: Regenerative endodontic treatment (RET) using a blood clot scaffold Group III: RET using a blood clot scaffold loaded with recombinant human BMPs (rhBMPs)
Eligibility Criteria
Inclusion Criteria:
* Patients aged 18-30 years
* Healthy patients with no systemic diseases or known allergic reactions
* Mature permanent molars diagnosed with pulp necrosis
* Presence of a medium sized periapical lesion confirmed clinically and radiographically (PAI=3,4,5)
Exclusion Criteria:
* Patients with generalized chronic periodontitis
* Presence of small periapical lesions (PAI=1,2)
* Periodontal pockets \> 3 mm
* Presence of systemic diseases or known hypersensitivity to any material used in the study
Source: ClinicalTrials.gov (NCT07700394). StuddyBuddy aggregates publicly available trial information.