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Completed
NCT07693673
Corneal Topography and High Order Aberrations in Regular Contraceptive Pills
Conditions: Cornea, Refraction Error
Sex: Female
Ages: 18 Years – 40 Years
Healthy volunteers: Yes
Enrollment: 40
Sponsor: Elshimaa A.Mateen
Location: Ophthalmology Department, Sohag University Hospital, Faculty of Medicine, Sohag University Sohag Sohag Governorate
Summary
Effect of regular usage of contraceptive pills on corneal topography and corneal high-order aberrations
Eligibility Criteria
Inclusion Criteria:
* Female participants aged 18-40 years.
* Prescribed combined oral contraceptive pills as part of routine gynecological care.
* Willing to undergo corneal topography/tomography before starting treatment and after 1 year.
* No previous history of corneal disease or ocular surgery.
* Able to provide informed consent.
Exclusion Criteria:
* Keratoconus or suspected corneal ectasia.
* Corneal opacity, dystrophy, degeneration, or scarring.
* Previous ocular surgery or significant ocular trauma.
* Current contact lens use or recent contact lens use without adequate discontinuation period.
* Active ocular surface disease or severe dry eye.
* Glaucoma, uveitis, retinal disease, or other significant ocular pathology.
* Diabetes mellitus, autoimmune disease, thyroid disease, pregnancy, or lactation.
* Use of other hormonal therapy or systemic medications known to affect corneal parameters.
Source: ClinicalTrials.gov (NCT07693673). StuddyBuddy aggregates publicly available trial information.