← Back to all trials
Not Yet Recruiting
NCT07687667
Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS
Conditions: Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, Female
Sex: Female
Ages: 18 Years – 40 Years
Healthy volunteers: No
Phase: NA
Enrollment: 406
Sponsor: Peking University Third Hospital
Location: Peking University Third Hospital Beijing Beijing Municipality
Summary
The goal of this clinical trial is to examine whether GLP1-RA and healthy lifestyle education in women with PCOS and obesity prior to fertility treatment improves live birth rate and other reproductive, maternal and perinatal outcomes compared to metformin plus healthy lifestyle education.
Eligibility Criteria
Inclusion Criteria:
* Women with a wish to conceive;
* Women with PCOS (Rotterdam criteria);
* 28 kg/m2≤BMI\5% weight loss in the last 3 months) or history of gastrointestinal surgery; Uterine abnormalities that may affect assisted reproductive outcomes, untreated hydrosalpinx Male azoospermia, severe oligozoospermia and asthenospermia, or patients receiving donor sperm treatment Chromosomal abnormalities, patients planning preimplantation genetic testing (PGT) or donor oocyte treatment History of recurrent miscarriag Allergic to or contraindicated for GLP-1 class medications.
Source: ClinicalTrials.gov (NCT07687667). StuddyBuddy aggregates publicly available trial information.
