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Enrolling By Invitation
NCT07677917
Preoperative Nebulized Dexmedetomidine Versus Nebulized Magnesium Sulphate in Reducing Emergence Agitation in Adult Undergoing Functional Endoscopic Sinus Surgery.
Conditions: Screening
Sex: All
Ages: 21 Years – 50 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 50
Sponsor: Ain Shams University
Location: Ain Shams University hospitals Cairo
Summary
Emergence agitation after sinus surgery is a common postoperative complication characterized by confusion, disorientation, and potentially violent behavior as a patient wakes from general anesthesia.This study compare the effect of nebulized dexmedetomidine versus nebulized magnesium sulphate in reducing emergence agitation in adult undergoing functional endoscopic sinus surgery.
This study aims to compare preoperative nebulized dexmedetomidine and nebulized magnesium sulphate in reducing emergence agitation in adult undergoing functional endoscopic sinus surgery.
Eligibility Criteria
Inclusion Criteria:
1. Adult patients between 21 and 50 years of age undergoing elective functional endoscopic sinus surgery.
2. American Society of Anesthesiologists physical status classification (ASA) I and II.
Exclusion Criteria:
1. Patient's refusal.
2. Complicated sinus surgery.
3. History of allergy to any of the study drugs.
4. Baseline HR≤60 beat/min.
5. Baseline mean arterial pressure (MAP)≤70 mmHg.
6. Psychiatric illness.
7. Cerebrovascular insufficiency.
8. Pregnancy.
Source: ClinicalTrials.gov (NCT07677917). StuddyBuddy aggregates publicly available trial information.
