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Available NCT07675057

Expanded Access for Vepugratinib (LY3866288) in Participants With Fibroblast Growth Factor Receptor 3 (FGFR3) Altered Solid Tumors

Conditions: Urinary Bladder Neoplasms, Neoplasm Metastasis, Carcinoma, Transitional Cell

Sex: All
Ages: 18 Years – N/A
Sponsor: Eli Lilly and Company

Summary

The treating physician/investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.

Eligibility Criteria

Inclusion Criteria: * Have metastatic urothelial carcinoma (UC) or other solid tumor with a qualifying fibroblast growth factor receptor 3 (FGFR3) genetic alteration. * Have exhausted other approved treatments, including erdafitinib for UC. * Are not eligible for an ongoing vepugratinib clinical trial Exclusion Criteria: * Currently enrolled in an ongoing clinical study of vepugratinib * Have a known severe (greater than or equal to (≥) Grade 3) hypersensitivity to any component or excipient of vepugratinib. * Current evidence of corneal keratopathy or retinal disorder confirmed by ocular examination. Exception: Individuals with asymptomatic ophthalmic conditions assessed by the investigator to pose minimal risk. * Significant cardiovascular disease: * Are pregnant, breastfeeding, or intent to become pregnant during the study or within 6 months of the last dose of study intervention.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07675057). StuddyBuddy aggregates publicly available trial information.