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Completed
NCT07668375
Outcome of Treatment With Botulinum toxinA in Patients With Temporomandibular Myofascial Pain
Conditions: Myofascial Pain - Dysfunction Syndrome of TMJ
Sex: All
Ages: 18 Years – 70 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 118
Sponsor: PAEC General Hospital, Islamabad
Location: PAEC General Hospital, Islamabad Islamabad Islamabad
Summary
Purpose: The aim of this study is to investigate the effectiveness and patient reported outcomes (interincisal distance and temporomandibular myofascial pain) of treatment with intramuscularly administered BTX-A vs N/S in patients with temporomandibular myofascial pain. OBJECTIVES: To determine the outcome of treatment with botulinum toxin-A vs N/S in patients with temporomandibular myofascial pain.
Eligibility Criteria
Inclusion Criteria:
* Patients presenting with temporomandibular myofascial pain (VAS ≥ 6) for more than one month will be included.
* Both genders.
* Age 18-70 years
Exclusion Criteria:
* Patient with history of allergic reactions with botulinum toxin-A.
* Medically compromised patients. Current pregnancy.
* Use of medication by the patients that could interfere with the effect of botulinum toxin-A (gentamycin, baclofen, atropine, revastigmine, verapamil, succinylcholine)
* Neuromuscular disorders.
Source: ClinicalTrials.gov (NCT07668375). StuddyBuddy aggregates publicly available trial information.
