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NCT07663669
Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection
Conditions: Antibody-mediated Rejection in Kidney Transplant
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 31
Sponsor: Centre Hospitalier Universitaire de Besancon
Location: Centre Hospitalier Universitaire de Besançon Besançon
Summary
This study aims to describe, over a one-year period, the clinical, biological, and histological evolution of a cohort of kidney transplant recipients who developed antibody-mediated rejection and were treated with extracorporeal photopheresis.
Eligibility Criteria
Inclusion Criteria:
* Kidney transplant recipients followed at the University Hospitals of Besançon and Lille between September 1, 2016, and August 31, 2023
* Patients with antibody-mediated rejection (as confirmed by histological analysis of the renal biopsy)
* Rejection treated with extracorporeal photopheresis
* Subjects who do not object to the use of their personal data and/or biological samples
* Subjects affiliated with, or beneficiaries of, the French social security system
Exclusion Criteria:
* Patients with acute rejection
* Pregnant women, women in labor, or breastfeeding mothers
* Individuals deprived of liberty by judicial or administrative decision; individuals receiving compulsory psychiatric care; or individuals admitted to a healthcare or social institution for reasons other than research participation
* Minors
* Adults under legal protection or unable to provide informed consent
* Subjects without health insurance coverage
* Subjects currently within an exclusion period from another study, or as listed in the "national volunteer registry"
Source: ClinicalTrials.gov (NCT07663669). StuddyBuddy aggregates publicly available trial information.