Cascade Testing In Identifying At-risk Family Members Of Individuals With Familial Hypercholesterolemia (FH) In PCP

The purpose of this study is to evaluate the effectiveness of two models of cascade testing in identifying at-risk family members of individuals diagnosed with familial hypercholesterolemia (FH).

Inclusion Criteria: Index Patients: * Age ≥ 18 years. * Confirmed FH diagnosis using Dutch Lipid Clinic Network criteria \*or\* genetic confirmation. * Identified through REP or Tapestry databases. * Able and willing to provide informed consent. * At least one eligible first- or second-degree relative. * Access to and active use of email (computer literacy requirement). Relatives: * First- or second-degree relative of an enrolled index patient. * Age ≥ 1 year (minors require parental consent + assent). * Willing to participate and able to complete electronic consent (guardian-assisted if minor). * Access to and active use of email (guardian). Exclusion Criteria: Index Patients: * No confirmed FH diagnosis. * Insufficient clinical follow-up (\