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NCT07638319
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction.
Conditions: Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: EARLY_PHASE1
Enrollment: 30
Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL
Location: Clinica Dentária Egas Moniz Caparica Monte Da Caparica
Summary
The goal of this randomized clinical trial is to assess whether β-TCP improves alveolar ridge preservation in patients who need tooth extraction. The main question it aims to answer is whether using β-TCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing.
The main questions it aims to answer are:
Does β-TCP improve ridge preservation compared with natural healing?
Researchers will compare β-TCP grafted sockets to natural healing sockets to see if β-TCP better preserves ridge volume.
Participants will:
Have a tooth indicated for extraction.
Be assigned to either β-TCP or natural healing.
Undergo CBCT and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.
Eligibility Criteria
Inclusion Criteria:
* 18 years or older
* Acceptance of informed consent
* Type 1 or 2 extraction sockets (Elian et al. 2007)
Exclusion Criteria:
* Presence of active infection or severe inflammation in the intervention zone
* Relevant medical history that contraindicates implant surgery
* Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation
* Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
* Uncontrolled and /or untreated periodontal disease
* Heavy smokers (more than 10 cigarettes per day)
* Immunosuppression
Source: ClinicalTrials.gov (NCT07638319). StuddyBuddy aggregates publicly available trial information.