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Completed
NCT07637435
Role of Vascular Endothelial Markers in Predicting Renal Prognosis and Mortality in Patients Undergoing HD-AKI
Conditions: Acute Kidney Injury, Hemodialysis
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 170
Sponsor: Muğla Sıtkı Koçman University
Location: Mugla Sitki Kocman University Muğla Menteşe
Summary
The aim of this study was to evaluate the role of Activin A, Nostrin, and Angiopoetin-2 levels in predicting the prognosis of renal function and in-hospital and 6-month mortality in patients undergoing emergency hemodialysis treatment for acute kidney injury. The main questions it aims to answer are:
Acute renal injury is a clinical entity with very important consequences. Mortality and morbidity are high in patients requiring hemodialysis. This study aims to evaluate the predictive effects of certain biomarkers on outcomes such as short- and long-term monitoring of renal function, weaning or continuation of hemodialysis, in-hospital and 6-month mortality in these patients. In patients with an indication for emergency hemodialysis, the following levels will be measured before hemodialysis:
* Serum Activin A,
* Serum Nostrin,
* Serum Angiopoetin-2
Eligibility Criteria
Inclusion Criteria:
* Patients 18 years and older of age requiring hemodialysis for acute kidney injury
Exclusion Criteria:
* Patients under 18 years of age
* Patients under chronic renal replacement therapy
* Patients with a history of renal transplantation
Source: ClinicalTrials.gov (NCT07637435). StuddyBuddy aggregates publicly available trial information.