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NCT07635836
Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer
Conditions: Gastric Cancer (GC), Double-tract Reconstruction, Tubular Gastric Anastomosis
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: No
Phase: NA
Enrollment: 52
Sponsor: Qilu Hospital of Shandong University
Location: Qilu Hospital of Shandong University Jinan Shandong
Summary
This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertiary hospitals, who underwent either double-tract reconstruction (DTR) or tubular gastric anastomosis (TGA). Participants were divided into two groups based on the surgical procedure. We conducted a comparative analysis of postoperative outcomes by evaluating electronic medical records, postoperative gastroscopy, 24-hour esophageal pH monitoring, and relevant rating scales.
Eligibility Criteria
Inclusion Criteria:
* Pathologically confirmed gastric adenocarcinoma by biopsy
* Carcinoma of the upper gastric body or Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG), with a clinical stage of cT1-3N0-1M0
* Age 18-75 years, with a performance status (PS) score of 0-2
* Candidates for planned surgical resection, eligible for either double-tract reconstruction or tubular gastric anastomosis based on preoperative assessment
* No severe dysfunction of vital organs (liver, kidney, heart, lung, or brain), and no severe infection or uncontrolled chronic diseases
Exclusion Criteria:
* Presence of other malignant tumors or severe chronic diseases (e.g., severe diabetes mellitus, chronic kidney disease, decompensated cirrhosis, etc.)
* Preoperative endoscopic diagnosis of Barrett's esophagus
* Severe preoperative malnutrition (albumin \
Source: ClinicalTrials.gov (NCT07635836). StuddyBuddy aggregates publicly available trial information.