Mesotherapy for the Management of Myofascial Pain Syndrome

Temporomandibular joint disorders represent a complex and heterogeneous group of musculoskeletal conditions affecting the temporomandibular joint,masticatory muscles, and associated structures, frequently manifesting as chronic orofacial pain. Temporomandibular joint (TMJ) disorders encompass a group of conditions affecting the jaw joint and associated musculature, leading to pain, impaired function, and a diminished quality of life. These disorders arise from various etiologies, including trauma,degenerative conditions such as osteoarthritis, and systemic inflammatory diseases, emphasizing their multifactorial nature. Although the mechanism of action of mesotherapy in TMJ disorders involves delivering anti-inflammatory and analgesic agents directly to the affected area,the literature reveals a significant research gap regarding its efficacy and longterm benefits.

Inclusion Criteria: 1. patients between 18 - 60 years. 2. Patients who had a Diagnosis of TMD, with chronic pain, muscle spasms, myofascial pain syndrome lasting at least 3 months, and challenges while chewing. 3. Patients who have difficulty opening their mouths, cases where conservative treatment methods (physical, medical, or appliances) have failed. 4. Patients who have Bruxism - Exclusion Criteria: 1. Systemic Diseases such as uncontrolled Diabetes, uncontrolled hypertension disorders of coagulation (hemophiliacs, undergoing therapy with anticoagulants or antiplatelet agents, and cancer patients undergoing chemotherapy. 2. Patients with a history of Muscular dystrophies, Myasthenia Gravis, Polymyositis, Rheumatoid arthritis, Hypothyroidism, and Sarcoidosis 3. Patients with active Infections around the injection site. 4. Females who are pregnant or breastfeeding are excluded. 5. A patient who had a history of severe mental health disorders or neurological conditions affecting pain perception or compliance. 6. Patients with allergies to the components used in mesotherapy.