Join us at Health Research Day — June 6th at Canton Waterfront Park, Baltimore!   Learn More →
← Back to all trials
Recruiting NCT07626515

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in Generally Healthy Adult Chinese Participants

Conditions: Healthy Participants

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 36
Sponsor: Hoffmann-La Roche

Location: Peking University First Hospital Beijing

Summary

This is a Phase I, randomized, double-blinded, placebo-controlled, study to assess the safety, tolerability, and pharmacokinetics (PK) of enicepatide in generally healthy adult Chinese participants with body mass index (BMI) ≥23.0 kilograms per meter squared (kg/m\^2).

Eligibility Criteria

Inclusion Criteria: * No evidence of active or chronic disease as determined by detailed medical and surgical history and the results of a physical examination, vital signs, 12 lead electrocardiogram (ECG), or clinical laboratory tests * BMI ≥23 kg/m\^2 at screening * Agreement to adhere to the contraception requirements Exclusion Criteria: * History of acute or chronic pancreatitis * History of clinically significant gallbladder disease in the opinion of the investigator * History of significant active or unstable major depressive disorder (MDD) or other severe psychiatric disorder * History or presence of an abnormal ECG that is deemed clinically significant in the opinion of the investigator * Clinically significant abnormalities (as judged by the investigator) in laboratory test results * History or presence of clinically significant cardiovascular disease, renal disease, hepatic disease, gastrointestinal disease, hematological disease, immunological disease, neurological disease, endocrine disease, metabolic disease, pulmonary disease, or history of any of these diseases with renal, hepatic, or cardiopulmonary dysfunction

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07626515). StuddyBuddy aggregates publicly available trial information.