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NCT07625046
How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes
Conditions: Pre Diabetic
Sex: Female
Ages: 30 Years – 50 Years
Healthy volunteers: No
Phase: NA
Enrollment: 5
Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology
Location: Illinois Tech Chicago Illinois
Summary
The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours. The study is also done to know if polyphenols will help a hormone called insulin work better in the body, so to look further into the possibility of figs being a functional food for the pre-diabetic population.
Eligibility Criteria
Inclusion Criteria:
* Be between 30-50 years old.
* Have a BMI of 25-35 kg/m².
* Have fasting blood glucose between 100-125 mg/dL or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
* Be non-smokers for at least 12 months.
* Be generally healthy, with no major organ-related diseases.
* Not take medications or supplements that could interfere with the study.
* Be able to follow study procedures, including dietary restrictions and scheduled visits
Exclusion Criteria:
* Smoker
* Vegetarian
* Taking over the counter supplements (e.g. fiber supplements, probiotics and/or prebiotics, antioxidants, anti-inflammation) and/or taking prescription medications that may interfere with study procedures or endpoints (e.g. Gastrointestinal medications, antibiotics) within the last 30 days
* Have cancer other than non-melanoma skin cancer in previous 5 years
* Taking unstable dose of hormonal contraceptive and/or stable dose less than 6 months
* Planning to become pregnant
* Pregnant and/or breast-feeding
* Excessive exercisers or trained athletes
* Excessive coffee/tea drinker
* Donated blood within last 3 months
* Have allergies/intolerances to foods consumed in the study
* Regular consumption of dried fruits exceeds \> 2 servings per day
* Actively losing weight/ trying to lose weight (unstable body weight fluctuations of \> 5 lbs in 3 months)
* Addicted to drugs or alcohol or have significant psychiatric or neurological disturbances
* Past smokers may be allowed in the study if stopped \>2 years
Source: ClinicalTrials.gov (NCT07625046). StuddyBuddy aggregates publicly available trial information.