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Active Not Recruiting
NCT07624591
Advanced Platelet-Rich Fibrin and Coronally Advanced Flap for Gingival Recession Treatment
Conditions: Gingival Recession
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 11
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City
Location: Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City
Summary
The goal of this clinical trial is to learn if adding a natural healing material works better to treat receding gums in adults. Receding gums is a condition where the gum tissue pulls back and exposes the tooth root. The main questions it aims to answer are:
* Does the addition of this healing material help cover the exposed root better than the standard surgery?
* Does the material help the gum tissue heal faster and become thicker? Researchers will compare a standard gum surgery alone to the standard gum surgery combined with Advanced Platelet-Rich Fibrin (A-PRF). A-PRF is a healing material made directly from the participant's own blood during the surgery. This comparison will help see if A-PRF improves the final cosmetic look and gum health.
Participants will:
* Have their blood drawn at the start of the surgery to create the A-PRF material.
* Receive the gum surgery with or without the A-PRF material. Visit the clinic for checkups and gum measurements at 1 week, 2 weeks, 4 weeks, 1 month, 3 months, and 6 months after the surgery.
Eligibility Criteria
Inclusion Criteria:
* Patients aged 18 years or older.
* Presence of 1 to 2 gingival recession defects requiring treatment, classified as RT1 (Cairo 2011).
* Gingival recession defects located in the anterior or premolar regions of the maxilla or mandible.
* Gingival thickness ≥ 1 mm. Keratinized tissue width ≥ 2 mm. Probing depth ≤ 2 mm.
* Good oral hygiene, demonstrated by a mean Gingival Index (GI) ≤ 1 and a mean full-mouth Plaque Index (PI) ≤ 1.
Exclusion Criteria:
* Patients with systemic diseases affecting wound healing (e.g., diabetes mellitus, coagulation disorders).
* Pregnant or lactating women.
* Patients with a smoking habit.
* Teeth with interproximal bone loss.
* Severely malpositioned teeth.
* Presence of caries or cervical restorations at the experimental site.
* History of previous periodontal surgery at the selected sites.
Source: ClinicalTrials.gov (NCT07624591). StuddyBuddy aggregates publicly available trial information.
