GLP-1 RA Cessation and Gastric Ultrasound Findings

This prospective observational study will evaluate the association between the time interval since the last dose of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and residual gastric contents before elective surgery. Adult patients receiving GLP-1 RAs and scheduled for elective non-cardiac surgery under general anesthesia will undergo preoperative point-of-care gastric ultrasound. The study will assess whether longer GLP-1 RA cessation intervals are associated with lower ultrasound-estimated gastric volume and a lower frequency of high-risk gastric contents. Body mass index will also be evaluated as a potential modifier of this association.

Inclusion Criteria: * Adults aged 18 years or older. * Patients receiving a glucagon-like peptide-1 receptor agonist. * Patients scheduled for elective non-cardiac surgery requiring general anesthesia. * Patients able to provide written informed consent. Exclusion Criteria: * Emergency surgery. * History of prior gastric surgery. * Known gastroparesis or severe gastroesophageal reflux disease. * Declined or unable to provide written informed consent.