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Active Not Recruiting NCT07613697

Postoperative Opioid Consumption of Serratus Posterior Superior Intercostal Plane Block Versus Thoracic Paravertebral Block

Conditions: Opioid Consumption, Postoperative

Sex: All
Ages: 21 Years – 75 Years
Healthy volunteers: No
Phase: NA
Enrollment: 48
Sponsor: Zagazig University

Location: Zagazig university hospitals Zagazig Sharqia Province

Summary

Previous studies found that paravertebral and thoracic epidural continuous infusions of opioid-free local anaesthetic were found to be comparable, but paravertebral analgesia (PVA) was associated with less respiratory complications and hypotension. The newly emerging Serratus posterior superior intercostal plane block (SPSIPB) provided excellent analgesia in most studies that have focused on video-assissted thoracoscopic surgery (VATS) and breast surgery. The aim of this clinical trial is to achieve better high quality pain control with less opioid consumption either by Serratus Posterior Superior Intercostal Plane Block (SPSIPB) or Thoracic Paravertebral Block after Open thoracotomy. This study will assess and compare the analgesic efficacy of both blocks to reduce opioid consumption, the efficacy of both blocks on postoperative respiratory functions after open thoracotomy. The main question it aims to answer is: Is there a difference between Serratus Posterior Superior Intercostal Plane Block (SPSIPB) and Thoracic Paravertebral block following open thoracotomy as regard postoperative opioid consumption, postoperative pain score, and postoperative respiratory functions? All patients will take a single dose of local anesthesia either through serratus posterior superior intercostal plane block (SPSIPB) or thoracic paravertebral block and the end of open thoracotomy then total opiod consumption willbe recorded after 24 hours postoperatively.

Eligibility Criteria

Inclusion Criteria: * BMI (18.5-35kg/m²). * Physical status: ASA I-II - III. * Patients undergoing posterolateral thoracotomy for lung resection. Exclusion Criteria: * Emergency surgeries. * Uncooperative patient. * History of allergy to study drugs. * Patients with coagulation disorders, advanced hepatic, renal, cardiovascular, respiratory disease and neuropsychiatric disorders (e.g. Alzheimer, Dementia, Delirium, mental retardation and cognitive dysfunction). * Infection at the site of block .

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07613697). StuddyBuddy aggregates publicly available trial information.