Intravenous Lidocaine for Postoperative Fatigue After Laparoscopic TAPP Inguinal Hernia Repair

This prospective randomized placebo-controlled trial aims to evaluate the effect of perioperative intravenous lidocaine on postoperative fatigue in patients undergoing elective laparoscopic TAPP inguinal hernia repair. Participants will be randomly assigned to receive either intravenous lidocaine or an equal-volume 0.9% sodium chloride placebo. The primary outcome is postoperative physical fatigue assessed using the Physical Fatigue subscale of the Multidimensional Fatigue Inventory-20 (MFI-20). Secondary outcomes include postoperative pain, cumulative tramadol consumption, postoperative nausea and vomiting, and the requirement for additional analgesia.

Inclusion Criteria: * Age 18 to 65 years * Scheduled for elective laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair * American Society of Anesthesiologists (ASA) physical status I or II * Able to understand and complete the Multidimensional Fatigue Inventory-20 (MFI-20) * Written informed consent provided Exclusion Criteria: * Known allergy or hypersensitivity to lidocaine or other amide-type local anesthetics * Clinically significant hepatic or renal dysfunction * Clinically significant cardiac rhythm or conduction disorder * Chronic opioid use * Regular use of antiarrhythmic medication * Pregnancy or breastfeeding * Planned use of an additional local anesthetic technique during the study intervention * Inability to complete the study assessments