Emulation of the RECORD3 Trial Using Healthcare Claims Data

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 149248

Sponsor: Brigham and Women's Hospital

Summary

Investigators are building an empirical evidence base for real-world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real-world data analyses can be conducted with confidence and how to implement such studies.

Eligibility Criteria

Inclusion Criteria: * At least 18 years of age * Scheduled to undergo elective total knee replacement Exclusion Criteria: * Pregnancy or breastfeeding * Had active bleeding or high risk of bleeding * Had contraindications for prophylaxis with enoxaparin * Drug or alcohol abuse * Concomitant use of protease inhibitors for the treatment of HIV * Had planned intermittent pneumatic compression * Had a requirement for anticoagulant therapy that could not be stopped * Substantial liver disease * Severe renal impairment (creatinine clearance \

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07599384). StuddyBuddy aggregates publicly available trial information.