A Trial to Evaluate the Long-term Safety and Tolerability of HRS-5965 in Patients With Primary IgA Nephropathy

This study aims to evaluate the long-term safety of HRS-5965 capsules in patients with primary IgA nephropathy, and also to assess its efficacy in reducing 24-hour urinary protein and delaying the decline in eGFR in these patients.

Inclusion Criteria: 1. Patients with primary IgA nephropathy who completed treatment in Study HRS-5965-305, or who prematurely discontinued study drug during the maintenance phase following initiation of rescue therapy; 2. Understand the research procedures and methods, voluntarily participate in this trial and sign the informed consent form in person. Exclusion Criteria: 1. Hypersensitivity to the study drug or its components； 2. History of immunodeficiency disorders； 3. History of invasive encapsulated bacterial infection； 4. History of malignant neoplasm； 5. The estimated glomerular filtration rate (eGFR) is less than 20 mL/min/1.73m2；