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Completed NCT07567924

Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain Syndrome

Conditions: Post Mastectomy Pain Syndrome

Sex: Female
Healthy volunteers: No
Phase: PHASE4
Enrollment: 158
Sponsor: Subas Ali

Location: Sindh Institute of urology and Transplantation Karachi

Summary

The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing mastectomy or breast-conservation (BCS). It could be burning, stabbing, shooting pain or pins-and-needle sensation. Participants will: * Take their prescribed allotted medicine for 14 days. * Will visit the clinic at 2 and 6 week interval for assessment.

Eligibility Criteria

Inclusion Criteria: * All diagnosed cases of post mastectomy pain syndrome * Patients developing radiation dermatitis grade 0 and 1 Exclusion Criteria: * Patient undergoing toilet mastectomy * Patient developing radiation dermatitis grade 2, 3 and 4 * Patients with convulsions * Patients with known pregabalin hypersensitivity (lightheadedness , sedation , double vision ,increase in bodyweight and imbalance) * Patients with known acetaminophen hypersensitivity (urticaria, bronchospasm, anaphylaxis) * Patients with renal failure * Patients with hepatic dysfunction/ hepatic disease * Patients with prior use of pregabalin due to chronic pain conditions within 3 months * Pregnant or lactating * Neuropsychiatric disorders

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07567924). StuddyBuddy aggregates publicly available trial information.