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Not Yet Recruiting NCT07565207

Effect of aiTBS on Intrinsic Spectral Dynamics and Task Performance

Conditions: Brain Plasticity

Sex: All
Ages: 18 Years – 50 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 80
Sponsor: University of Pennsylvania

Summary

Aim 1: Measure local shifts in cortical spectral dynamics following aiTBS. Aim 2: Measure network-specific shifts in task performance following aiTBS. Exploratory aim: Evaluate changes to resting state spectral dynamics in absence of stimulation after aiTBS.

Eligibility Criteria

Inclusion Criteria: * Able to give their consent * Right-handed or ambidextrous Exclusion Criteria: * Non-english speaking * Current or past non-anxiety-related psychiatric comorbidity. * Active or history of active suicidal ideation * Alcohol/drug problems in the past year or lifetime alcohol or drug dependence * Medications that act on the central nervous system * History of seizure * History of epilepsy * Increased risk of seizure for any reason * Pregnancy, or positive pregnancy test * Any medical (e.g., stroke, breathing problems, motion disorders) or neurological (e.g., a significant brain injury or brain infection history that increases seizure risk) condition that increases risk for fMRI or TMS (Protocol will follow recommendations from Rossi et al. 2021 doi:10.1016/j.clinph.2020.10.003) * Any metal in their body which would make having an MRI scan unsafe * Any sort of medical implants * Hearing loss * Claustrophobia * orthostatic hypotension

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07565207). StuddyBuddy aggregates publicly available trial information.