Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

Conditions: Intracranial Pressure, Laparoscopic Surgery, Optic Nerve Sheath Diameter

Sex: Female

Ages: 18 Years – 85 Years

Healthy volunteers: No

Phase: NA

Enrollment: 63

Sponsor: Medipol University

Summary

Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.

Eligibility Criteria

Inclusion Criteria: * Patients planned for laparoscopic hysterectomy bilateral oophorectomy surgery under general anesthesia. * ASA physical status I-II Exclusion Criteria: * Patients receiving beta-blocker or diuretic treatment. * Patients with severe heart failure. * Patients diagnosed with diabetes with ocular or neurological complications. * Patients who have undergone cardiac surgery, eye surgery, brain surgery, or thoracic surgery. * Patients with a history of hydrocephalus, glaucoma, intracranial mass, and stroke. * History of allergy to the study drugs * Known or suspected pregnancy

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07525648). StuddyBuddy aggregates publicly available trial information.