Guangdong Endometriosis Retrospective Clinical Cohort

This retrospective cohort study evaluates the association between postoperative hormonal treatment and recurrence of ovarian endometriosis in women undergoing surgery for ovarian endometrioma. The study includes patients treated at a single center who initiated one postoperative hormonal regimen after surgery. The main objective is to compare the risk of recurrence among women receiving combined oral contraceptives, gonadotropin-releasing hormone agonists, dienogest, or dydrogesterone. Recurrence is assessed during follow-up based on postoperative clinical and ultrasound findings. The results may help clarify the comparative effectiveness of commonly used postoperative hormonal strategies for reducing recurrence after surgery for ovarian endometrioma.

Inclusion Criteria: * Female patients who underwent conservative surgery for ovarian endometrioma at the study center. * Initiation of one postoperative hormonal regimen within 1 month after surgery. * Continuous use of the same single hormonal regimen for at least 6 months after surgery. * Availability of clinical records and postoperative follow-up data for assessment of study outcomes. Exclusion Criteria: * Failure to initiate postoperative hormonal therapy within 1 month after surgery. * Discontinuation of the postoperative hormonal regimen before 6 months. * Use of sequential or multiple postoperative hormonal therapies during the initial treatment period. * Incomplete clinical records or insufficient follow-up data for evaluation of recurrence.