Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health

Conditions: Atherosclerosis Cardiovascular Disease, Metabolic Syndrome, Dyslipidaemia, Endothelial Dysfunction

Sex: All

Ages: 25 Years – 60 Years

Healthy volunteers: Yes

Enrollment: 90

Sponsor: Liverpool John Moores University

Location: Tom Reilly Building, Liverpool John Moores University Liverpool ENG

Summary

This study aims to investigate the extent to which vegan or plant-based, omnivorous, and carnivore dietary patterns affect LDL aggregation susceptibility (the affinity for LDL cholesterol particles to clump together in the blood), which may promote plaque build-up in arteries. Using a cross-sectional mixed-methods design, the study will measure LDL aggregation, blood lipids, and other metabolic biomarkers in individuals following these diets, and combine these data with dietary and behavioural information to examine links with cardiovascular and metabolic health.

Eligibility Criteria

Inclusion Criteria: * Adults aged 25-60 years. * BMI range (18.5-29.9 kg/m²). * Following one of the specified dietary patterns (vegan/plant-based, carnivore, or omnivorous) for a minimum of 6 months. * Self-identified as health-focused (i.e., intentionally following the diet for perceived health benefits). Exclusion Criteria: * BMI outside the stated range (\

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07474233). StuddyBuddy aggregates publicly available trial information.