Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)

Conditions: Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection, Conditioned Serum

Sex: All

Ages: 40 Years – 80 Years

Healthy volunteers: No

Phase: NA

Enrollment: 60

Sponsor: Pamukkale University

Location: Pamukkale University Hospital Pamukkale Denizli

Summary

The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared

Eligibility Criteria

Inclusion Criteria: 1. Diagnosis of knee osteoarthritis according to ACR criteria at least 6 months ago. 2. Being between grade 1-2 according to the Kellgren-Lawrence radiological classification. 3. Not having had PRP injection in the last year. 4. Knee pain ≥ 5 according to the visual pain scale. Exclusion Criteria: 1. Those with significant neurological or cardiovascular disorders. 2. Those with active thrombovascular disease. 3. Those with joint or skin infections. 4. Those who have recently had an infectious disease. 5. Those infected with Hepatitis B, C, and HIV. 6. Those who have received intra-articular knee injections (hyaluronic acid, PRP, corticosteroids, and others) within the last year. 7. Those who use oral corticosteroids. 8. Those who have used NSAIDs within the last week. 9. Those who have used anti-platelet or anti-aggregant drugs within the last week. 10. Those with coagulation disorders. 11. Those with hemoglobin \

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Source: ClinicalTrials.gov (NCT07473232). StuddyBuddy aggregates publicly available trial information.