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Completed
NCT07443085
Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery
Conditions: Delirium - Postoperative
Sex: All
Ages: 55 Years – 70 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 75
Sponsor: Benha University
Location: Benha university Banhā Al Qalyobia
Summary
This study evaluates the dose-response relationship of Dexmedetomidine (DEX) in reducing the incidence and severity of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) in elderly patients. The study compares different doses of DEX against a fentanyl control group in patients undergoing major lower limb orthopedic surgery under general anesthesia to determine the optimal dosage for cognitive protection.
Eligibility Criteria
Inclusion Criteria:
* Elderly surgical patients.
* ASA physical status grade II-III.
* Planned major lower limb orthopedic surgery.
Exclusion Criteria:
* pre-existing dementia or drug allergies
Source: ClinicalTrials.gov (NCT07443085). StuddyBuddy aggregates publicly available trial information.