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Completed NCT07443085

Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery

Conditions: Delirium - Postoperative

Sex: All
Ages: 55 Years – 70 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 75
Sponsor: Benha University

Location: Benha university Banhā Al Qalyobia

Summary

This study evaluates the dose-response relationship of Dexmedetomidine (DEX) in reducing the incidence and severity of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) in elderly patients. The study compares different doses of DEX against a fentanyl control group in patients undergoing major lower limb orthopedic surgery under general anesthesia to determine the optimal dosage for cognitive protection.

Eligibility Criteria

Inclusion Criteria: * Elderly surgical patients. * ASA physical status grade II-III. * Planned major lower limb orthopedic surgery. Exclusion Criteria: * pre-existing dementia or drug allergies

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07443085). StuddyBuddy aggregates publicly available trial information.