Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea

This observational study is being undertaken as a part of a Master of Research (MRes) in Clinical Research programme. Its goal is to learn about how continuous positive airway pressure (CPAP) therapy changes the complexity of body signals in adults with obstructive sleep apnoea (OSA). The main question it aims to answer is: \- How does the complexity of physiological signals (specifically oxygen saturation, heart rate, and heart rate variability) change in adults with OSA from before to after three and six months of CPAP treatment? It will use data from individuals who took part in an earlier trial, called 3DPiPPIn, which tested the use of 3D-printed, customised masks CPAP masks through sleep studies.

Inclusion Criteria: * Participation in the 3DPiPPIn trial * Completion of the 3DPiPPIn trial to its primary endpoint of six months * Availability of physiological signal data at baseline, three months, and six months * Provision of informed consent permitting the use of their data in future research Exclusion Criteria: * Non-completion of the 3DPiPPIn trial to its primary endpoint of six months * Missing physiological signal data at baseline, three months, or six months * No consent for the use of their data in future research