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NCT07386262
A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic Stroke
Conditions: Cerebral Edema, Ischemic Stroke, Acute, Malignant Cerebral Edema, Anterior Circulation Brain Infarction
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 10
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
Location: The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang
Summary
The primary objective is to investigate whether treatment with Adacolumn can ameliorate the progression of cerebral edema within 72 hours in patients with anterior circulation ischemic stroke. The secondary objective is to explore if Adacolumn could improve acute neurologic status, functional outcomes, treatment requirements and safety in patients with anterior circulation ischemic stroke.
Eligibility Criteria
Inclusion Criteria:
1. Age 18-80 years, regardless of gender;
2. A clinical diagnosis of acute ischemic stroke;
3. Proven large vessel occlusion in ICA or MCA-M1 occlusion (carotid occlusions can be cervical or intracranial, with or without tandem MCA lesions) determined by MRA or CTA or DSA;
4. NIHSS score ≥10 at screening;
5. Pre-stroke mRS score \
Source: ClinicalTrials.gov (NCT07386262). StuddyBuddy aggregates publicly available trial information.
