Molecular and Cellular Characterization of MALT Lymphoma

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 400

Sponsor: International Extranodal Lymphoma Study Group (IELSG)

Summary

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an slow growing malignancy characterized by marked biological and clinical differences across different anatomical sites. Using participants' samples and clinical information, this observational and non-interventional research aims to generate a comprehensive molecular and cellular atlas of MALT lymphoma. The results will enable the identification of biologically meaningful tumor subtypes, microenvironmental niches, and candidate biomarkers with potential relevance for the diagnosis, prognosis, and therapy of MALT lymphoma.

Eligibility Criteria

Inclusion Criteria: 1. Male or female adults 18 years or older 2. Diagnosis of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue on histology after Jan 1st, 2000. 3. Availability of tumor material from biopsies (either frozen or formalin-fixed paraffin-embedded) (FFPE). 4. Availability of the baseline and follow-up annotations. Exclusion Criteria: * None

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07376330). StuddyBuddy aggregates publicly available trial information.