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NCT07372859
Women's Heart: Impact of Ultra-endurance and Hormonal Profile on Cardiac and Systemic Inflammatory Parameters in Female Runners
Conditions: Healthy Volunteer
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 120
Sponsor: French Cardiology Society
Location: Hôpital Henri Mondor, APHP Créteil
Summary
The goal of this clinical trial is to describe the cardiac and systemic inflammatory adaptations specific to women practicing ultra-endurance sports.
The objectives are to:
* Improve the understanding of cardiac and systemic inflammatory adaptations specific to women participating in ultra-endurance sports.
* Assess the relationship between observed cardiac and systemic inflammatory alterations and the relative levels of estrogen, testosterone, and progesterone.
* Describe the vascular adaptations specific to women participating in ultra-endurance sports.
* Examine the influence of defense mechanisms on the emotional dynamics observed during and after an ultra-endurance race.
Eligibility Criteria
Inclusion Criteria:
* Must have a Global Positioning System watch during the race;
* Must participate in one of the following races:
* "Ecotrail de Paris Ile France©" (=a trail running race in the Paris region, it is not possible to translate; it is a registered trademark) 80 kilometers;
* Or "la 6000D©" 69 kilometers;
* Must comply with the race regulations:
* Medical certificate stating no contraindications to competitive running, dated less than 12 months prior to the race;
* Or a valid sports license on the day of the race.
* Must agree to participate in the study, sign the consent form, and allow the sponsor to use their data for the purposes of this study.
Exclusion Criteria:
* Refusal or linguistic or mental incapacity to sign the informed consent form;
* Person under guardianship (conservatorship, curators, or legal protection) or deprived of liberty;
* Person not affiliated with a social security scheme;
* Pregnant woman;
* Person participating in a drug study;
* Women with a medical history (chronic lung disease, heart disease, pharmacologically treated hypertension) or with a known significant chronic inflammatory disease at the time of the enrollment visit;
* Person who has already participated in this study in a previous race.
Source: ClinicalTrials.gov (NCT07372859). StuddyBuddy aggregates publicly available trial information.