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NCT07359131
Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery
Conditions: Temporomandibular Joint Disorders
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: No
Enrollment: 700
Sponsor: Jingping Wang, MD, Ph.D.
Location: Meikun Wang Boston Massachusetts
Summary
The goal of this observational study is to evaluate postoperative outcomes following temporomandibular joint (TMJ) surgery and to compare the effectiveness of intraoperative platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) injections in patients with temporomandibular joint disorders.
The study includes adult patients who underwent TMJ surgery and received either PRP or PRF intraoperatively. The main questions this study aims to answer are:
Whether intraoperative PRP or PRF injection is associated with differences in postoperative pain intensity and recovery.
Whether PRP and PRF differ in their effects on postoperative jaw function, including maximum mouth opening and joint symptoms.
If there is a comparison group: Researchers will compare patients who received intraoperative PRP with those who received intraoperative PRF to assess differences in postoperative pain, functional outcomes, and joint-related symptoms.
Participants will:
Have their existing medical records reviewed retrospectively.
Provide postoperative outcome data derived from routine clinical follow-up, with no prospective recruitment or intervention.
Eligibility Criteria
Inclusion Criteria:
Patients aged 18 to 75 years (inclusive)
Underwent unilateral or bilateral temporomandibular joint (TMJ) arthroscopy
Received intraoperative platelet-rich plasma (PRP) or platelet-rich fibrin (PRF) injection during TMJ arthroscopy
Exclusion Criteria:
Age younger than 18 years or older than 75 years
Did not undergo TMJ arthroscopy
Did not receive intraoperative PRP or PRF injection
Incomplete clinical or follow-up data
Source: ClinicalTrials.gov (NCT07359131). StuddyBuddy aggregates publicly available trial information.