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Recruiting
NCT07352306
Topical Diacerein in Psoriasis Vulgaris
Conditions: Psoriasis Vulgaris
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE4
Enrollment: 60
Sponsor: Alaa Ashraf Muhammad Helal
Location: Kasr Al-Ainy Psoriasis Unit Cairo
Summary
The goal of this clinical trial is to evaluate the safety and effectiveness of topical diacerein in adults with psoriasis vulgaris. The primary objective of the study is to compare the proportion of participants who achieve a clinically meaningful improvement in disease severity between the topical diacerein group and the placebo group.
Participants will:
Be assigned to receive topical diacerein 1% or placebo twice daily for a treatment period of 2 months.
Attend follow-up visits at Weeks 2, 4, 6, and 8. Undergo an additional evaluation one month after treatment cessation.
Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years old of both genders.
* Patients with mild chronic plaque psoriasis body surface area (BSA \< 10%) along with Psoriasis Area and Severity Index (PASI) score of \< 10, and/or Dermatology Life Quality Index (DLQI) score of \
Source: ClinicalTrials.gov (NCT07352306). StuddyBuddy aggregates publicly available trial information.