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Active Not Recruiting NCT07346326

Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction

Conditions: Anterior Cruciate Ligament Injuries

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 64
Sponsor: Khyber Medical University Peshawar

Location: Khyber Teaching Hospital Peshawar KPK

Summary

This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT) autograft or a Hamstring Tendon (HST) autograft. The primary objective is to compare early functional outcomes between the two groups at 6 weeks and 3 months post-surgery, using the Lysholm Knee Score. The study aims to demonstrate the non-inferiority of the PLT graft. All surgeries will be performed arthroscopically at Khyber Teaching Hospital, Peshawar, followed by a standardized rehabilitation protocol.

Eligibility Criteria

Inclusion Criteria: * Patients aged 18 years or older. * Isolated, primary Anterior Cruciate Ligament (ACL) injury confirmed by clinical assessment and Magnetic Resonance Imaging (MRI). * Provides written informed consent for the surgical procedure and study participation, including follow-up assessments. Exclusion Criteria: * Multiligament knee injuries (e.g., concomitant PCL, MCL, or LCL injuries). * Previous surgery or history of fracture in the involved lower limb. * Radiographic evidence of osteoarthritis in the affected knee. * Presence of any neuromuscular disease.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07346326). StuddyBuddy aggregates publicly available trial information.