Ultra-processed Food Consumption and Health Pilot Study | Clinical Trial | StuddyBuddy@endsection
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Recruiting
NCT07318064
Ultra-processed Food Consumption and Health Pilot Study
Conditions: Obesity & Overweight
Sex: All
Ages: 18 Years – 50 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 6
Sponsor: Pennington Biomedical Research Center
Location: Pennington Biomedical Research Center Baton Rouge Louisiana
Summary
The objective of this study is to explore the effects of two dietary conditions (UPF-diet and typical American diet) on a number of clinical and metabolic outcomes in order to derive sample size estimates for a larger trial and to determine the feasibility of the study approach.
This study is an out-patient cross-over trial comparing the Nutrition for Precision Health (NPH) purple diet (American Diet) and a diet high in ultra-processed foods (UPF diet) for two weeks in which participants will be randomized to the order of the diets.
Specific Aim 1: Determine the feasibility of recruiting, enrolling and assessing participants in a randomized trial comparing a UPF diet with the standard American diet. Feasibility will be assessed by the achievement of study goals (i.e., sample size; completeness of study data).
Specific Aim 2: Derive sample size estimates for future trials based on the mean effects and associated variances obtained in the pilot study.
Eligibility Criteria
Inclusion Criteria:
* Overweight or obesity (BMI 25-50 kg/m2)
* Willingness to accept group assignment and provide outcome measures
* Premenopausal (women only)
* Be able to communicate (oral and written) in English
* Be able to provide informed consent
Exclusion Criteria:
* Recent weight loss (≥10 pounds in the last six months)
* On a regimen of medications (weight loss or otherwise) that can affect weight or diabetes outcomes for less than 3 months (GLP1 medications allowed if weight stable and on stable dose for \>=3 months)
* Given birth within the past year or is currently pregnant or breastfeeding
* Past bariatric surgery (\
Source: ClinicalTrials.gov (NCT07318064). StuddyBuddy aggregates publicly available trial information.