The Effectiveness of Pain Neuroscience Education for Patients With Carpal Tunnel Syndrome

The goal of this clinical trial is to investigate the effects of Pain Neuroscience Education applied in the treatment of mild and moderate carpal tunnel syndrome (CTS). The main question it aims to answer is: Does PNE have a therapeutic effect on carpal tunnel syndrome in clinical and ultrasonographic terms? Researchers will compare whether PNE creates a synergistic effect alongside home based exercise programs and splint application in mild to moderate CTS, and will objectively demonstrate potential benefits such as relief from pain and numbness.

Inclusion Criteria: * Being 18 years of age or older * Having a diagnosis of mild or moderate CTS confirmed by ENMG * Having complaints of pain and numbness in the first three fingers of the hand for at least 3 months Exclusion Criteria: * Presence of severe CTS findings on electrophysiological examination * Presence of metabolic diseases such as uncontrolled diabetes and hypothyroidism * Presence of inflammatory rheumatic disease (e.g., rheumatoid arthritis) * Presence of other neuromuscular diseases affecting the hand and wrist (Polyneuropathy, Cervical radiculopathy, peripheral nerve damage, Brachial plexus damage, other entrapment neuropathies, etc.) * History of hand and wrist trauma * History of neck and wrist surgery * History of steroid injection into the carpal tunnel within the last 3 months * History of physical therapy application to wrist within the last 3 months * Deformity preventing the use of a splint on the wrist * Previous participation in a program for the psychological management of chronic pain * Cognitive dysfunction preventing cooperation with tests