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Recruiting
NCT07287137
Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) Study
Conditions: COVID -19, COVID - 19, COVID 19, Influenza, Respiratory Virus, Respiratory Viruses, Respiratory Virus Infection, Respiratory Virus Infections
Sex: All
Ages: 18 Years – 79 Years
Healthy volunteers: Yes
Phase: PHASE4
Enrollment: 54
Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine
Location: Walter Reed National Military Medical Center Bethesda Maryland
Summary
CIRV2 is a Phase IV randomized, open-label, trial of FDA-approved COVID-19 and/or influenza vaccines (no more than minimal risk) with longitudinal follow-up. In 2026 CIRV2 will compare immunogenicity and reactogenicity of the recombinant Novavax COVID-19 vaccine and the mRNA Pfizer-BioNTech COVID-19 vaccine.
Eligibility Criteria
Inclusion Criteria
1. 18-79 years old
2. Have a history of any of the following risk factors for severe COVID:
Current:
* Age \> 65 years old
* Physical inactivity (defined as \
Source: ClinicalTrials.gov (NCT07287137). StuddyBuddy aggregates publicly available trial information.