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NCT07279948
Lung Cancer Screening Implementation Project in the Brazilian Public Health Care System (LUSIP)
Conditions: Lung Cancer
Sex: All
Ages: 50 Years – 80 Years
Healthy volunteers: No
Enrollment: 477
Sponsor: AstraZeneca
Location: Research Site Rio de Janeiro
Summary
A prospective, longitudinal, single-arm interventional study of lung cancer screening.
Eligibility Criteria
Inclusion Criteria:
In order, to be eligible for the study, patients must fulfill all the following inclusion criteria:
* Age between ≥50 and ≤80 years.
* Be a current smoker or have quit 15 years ago or less.
* Have participated or are currently participating in smoking cessation program.
* Lifetime smoking exposure equal to or greater than 20 pack-year.
* Provided signed informed consent (ICF)
Exclusion Criteria:
* In order, to be exclude for the study, patients must at least one of the following exclusion criteria:
* Contraindications to the screening examination: (claustrophobic or weighing more than 130 kgs).
* Inability to climb 3 stair steps non-stop (36 steps).
* Disabling dyspnea
* Symptomatic (with signs and symptoms suspicious of breast cancer lung, namely):
* pleuritic chest pain
* rapidly progressive dyspnea of recent onset
* hemoptysis
* unexplained hoarseness, lasting more than 1 month.
* bone pain
* supraclavicular lymphadenopathy or cervical lymphadenopathy persistent
* unexplained weight loss of 5% or more of weight in less than 6 months
* Previous history of malignant neoplasm (excluding non-melanoma skin cancer) diagnosed less than 10 years before the date of the interview;
* Patients with diagnostic of severe psychiatric disease
* Immunosuppressed by illness or drugs.
* Subjected to anterior lung resection even when determined due to an etiology other than malignant neoplasia.
* Person with a serious terminal illness that contraindicates curative lung surgery.
Source: ClinicalTrials.gov (NCT07279948). StuddyBuddy aggregates publicly available trial information.