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Recruiting
NCT07278323
Frozen Shoulder and Hormone Replacement Therapy
Conditions: Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Sex: Female
Ages: 40 Years – N/A
Healthy volunteers: No
Phase: PHASE4
Enrollment: 60
Sponsor: University of California, San Francisco
Location: UCSF Orthopaedic Institute San Francisco California
Summary
The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, stiffness, and progressive loss of range of motion. Age-related menstrual cycle changes, known as perimenopause and/or menopause, refers to a change or stoppage of monthly menstrual cycles. Other symptoms participants may be experiencing include vaginal dryness, hot flashes, or night sweats. Hormone replacement therapy (HRT) refers to medicine with female hormones in it. For this study, HRT will be in the form of a patch that goes on the skin and a daily oral pill. Participants will be randomly assigned to receive either HRT plus standard care, or only standard care. Follow-up tests will be completed at 6 months of treatment to assess participant progress.
Eligibility Criteria
Inclusion Criteria:
* Diagnosis of adhesive capsulitis of the shoulder
Exclusion Criteria:
* History of hormone sensitive cancer
* Bilateral adhesive capsulitis of the shoulder
* Currently using hormonal treatments including contraceptives
Source: ClinicalTrials.gov (NCT07278323). StuddyBuddy aggregates publicly available trial information.