New Diagnostic Criteria in the Evaluation Response to Ablation Treatment of Hepatocellular Carcinoma Nodules

Hepatocellular carcinoma (HCC) is a primary liver malignancy that typically develops in the setting of chronic liver disease with a cirrhotic background. Currently, one of the main imaging techniques used to evaluate space-occupying lesions in the splanchnic district is contrast-enhanced ultrasound (CEUS), which is characterized by high sensitivity and specificity in lesion characterization through the assessment of enhancement patterns following contrast administration. When an HCC nodule is small (\

Inclusion Criteria: * Age greater than 18 years; * HCC nodules treated with locoregional thermal ablation using RFA or MWA; * Signed informed consent. Exclusion Criteria: * Refusal to participate in the study; * Contraindications to performing post-treatment CEUS; * Absence of at least one CEUS examination during follow-up after locoregional thermal ablation with RFA or MWA; * Contraindications to performing post-treatment CT or MRI. * Absence of post-treatment CT or MRI follow-up imaging; * LR-TRA Nonevaluable categorization on post-treatment CT or MRI follow-up imaging.