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Not Yet Recruiting NCT07251647

Adaptation of the Mini-Mental State Examination (MMSE) for the Reunion Island Population

Conditions: Alzheimer s Disease, Vascular Cognitive Impairment

Sex: All
Ages: 60 Years – 89 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 400
Sponsor: Centre Hospitalier Universitaire de la Réunion

Location: CHU de La Réunion - site Nord - Geriatric department Saint-Denis

Summary

The Mini-Mental State Examination (MMSE) is the most widely used cognitive screening and monitoring test for neurocognitive disorders in current clinical practice. Its French version was published in 1998 by the GRECO group (MMSE-GRECO). However, some items of this French version are not adapted to local Reunionese particularities. The main objective is to propose and validate the psychometric properties of an adapted version of the MMSE, to the Reunionese culture (MMSE-RUN) in a healthy population and in a sick population (Alzheimer's Disease and Vascular Cognitive Disorder), and to compare its performance with the MMSE-GRECO.

Eligibility Criteria

Inclusion criteria: * For the healthy population : aged 60 to 89 years, residing in Reunion for more than 5 years, able to understand the test instructions, available for a one-hour interview, affiliated with a social security scheme, with informed consent. * For the sick population : aged 60 to 89 years, residing in Reunion for more than 5 years, presenting probable or possible Alzheimer's disease and/or probable vascular cognitive disorder, able to understand the test instructions, available for a one-hour interview, affiliated with a social security scheme, with informed consent. Exclusion criteria: * For the healthy populationhistory of neurological pathology, neurodegenerative pathology with cognitive expression, refusing to participate in the study, under legal protection. * For the sick population: acute unresolved medical decompensation or acute psychic decompensation, refusing to participate in the study, under legal protection.

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Source: ClinicalTrials.gov (NCT07251647). StuddyBuddy aggregates publicly available trial information.