A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer

The goal of this clinical trial is to learn if a tailored intervention can help make it easier for adolescents and young adults with cancer to take their medications. The main questions the researchers are trying to answer are: * Does the tailored intervention increase adherence? * Does the tailored intervention improve quality of life? * Does the tailored intervention reduce health care utilization? The researchers will compare the tailored intervention to a uniform standard of care intervention (an intervention designed to be similar to what is currently happening in clinical care) to see if the tailored intervention works to improve adherence. Participants will: * Use an electronic pill bottle or box to store their medication * Participate in intervention sessions * Complete surveys before the intervention, after the intervention, and 6-months later

Inclusion Criteria: * Patient is 15.00 to 24.99 years of age * Patient is diagnosed with cancer * Patient is prescribed an oral anticancer/antitumor agent or prophylaxis Exclusion Criteria: * Patient is not fluent in English * Patient evidences significant cognitive deficits * Patient's medical status or treatment precludes participation * Patient enrolled on a medical trial requiring medication storage in a trial-provided container * Patient demonstrates greater than or equal to 95% adherence during run-in period * Patient declines to use or has difficulty using electronic adherence monitoring device during run-in