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NCT07136519
Toripalimab, Induction Chemotherapy, Radiation Therapy With Omega-3 for Locally Advanced Nasopharyngeal Carcinoma
Conditions: Nasopharyngeal Carcinoma (NPC)
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 30
Sponsor: Affiliated Hospital of Guangdong Medical University
Location: Affiliated Hospital of Guangdong Medical University Zhanjiang Guangdong
Summary
The aim of this study is to evaluate the efficacy, adverse reactions, nutritional status analysis, and quality of life analysis of Toripalimab Plus Induction Chemotherapy Followed by Radiation Therapy Combined with Omega-3 in the treatment of locally advanced nasopharyngeal carcinoma.
Eligibility Criteria
Inclusion Criteria:
* Written informed consent can be provided, and understanding and compliance with research requirements and evaluation schedules are required.
* On the date of signing the informed consent form, the age range is between 18 and 65 years old (or the legal age specified by local laws).
* Pathological diagnosis is non keratinizing carcinoma of the nasopharynx (differentiated or undifferentiated, i.e. WHO classification II or III).
* Clinical staging is anyTN2-3M0 or T4N1M0 (AJCC8th/UICC staging).
* ECOG score is 0-1 points.
* Hemoglobin (HGB) ≥ 90g/L, white blood cell (WBC) ≥ 4.0 × 109/L, platelet (PLT) ≥ 100 × 109/L.
* Liver function: ALT and AST\
Source: ClinicalTrials.gov (NCT07136519). StuddyBuddy aggregates publicly available trial information.