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NCT07079852
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Conditions: Healthy
Sex: All
Ages: 21 Years – 45 Years
Healthy volunteers: Yes
Phase: PHASE1, PHASE2
Enrollment: 48
Sponsor: Manoj Doss
Location: The University of Texas at Austin Dell Medical School Austin Texas
Summary
This study will test the effects of psilocybin on memory and cognition in healthy participants using computerized tasks and magnetic resonance imaging (MRI).
Eligibility Criteria
Inclusion Criteria:
* 21 to 45-years-old.
* 3-30 lifetime psychedelic uses.
* English as a first language.
* High school education (or equivalent)
* Psychiatrically healthy (as assessed by the SCID-5).
* Medically healthy (as assessed by a physical examination and ECG).
* Willingness to attend all study sessions and complete all procedures.
* BMI between 19 and 30.
Exclusion Criteria:
* Current or past diagnosis of psychiatric disorders except panic attacks, depressive disorder, or anxiety, or disorder from ≥1 year prior.
* Current or past medical conditions that might interfere with study participation or be contraindicated for psilocybin administration (e.g., hypertension, history of stroke, cardiovascular disease, etc.)
* Current daily medications except birth control (females).
* Pregnant, nursing, or planning to become pregnant (assessed with urine pregnancy test).
* Ingestion of a psychedelic \
Source: ClinicalTrials.gov (NCT07079852). StuddyBuddy aggregates publicly available trial information.
