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NCT07073430
Development and Demonstration of a Precision Prevention and Treatment System for Colorectal Tubular Adenomas Lesions
Conditions: Colorectal Adenoma, Artificial Intelligence (AI)
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 4000
Sponsor: Renmin Hospital of Wuhan University
Location: Renmin Hospital of Wuhan University Wuhan Hubei
Summary
This study is a prospective,multi-center and observational clinical study.Investigators would like to innovatively construct a "trinity" database of colorectal tubular adenomas based on white light - magnifying chromo - pathological images.It simulates the decision - making logic of doctors, and based on the multimodal endoscopic LAFEQ method previously proposed, develop a multimodal deep - learning diagnostic model for colon adenomas and an interpretable risk prediction model for intestinal adenomas. While achieving high - precision auxiliary treatment decisions, clearly present the decision - making basis, and break through the limitation of poor interpretability of previous medical imaging AI models.
Eligibility Criteria
Inclusion Criteria:
* Patients aged ≥ 18 years, who need to undergo colonoscopy, regardless of gender.
* Voluntarily sign the informed consent form
* Promise to abide by the research procedures and cooperate in the implementation of the entire research process.
Exclusion Criteria:
* Patients who has a history of abdominal or pelvic surgery or radiotherapy in the past;
* Patients who has definite active lower gastrointestinal bleeding.
* Existing or suspected hereditary colorectal polyposis, inflammatory bowel disease;
* Uncontrolled hypertension (systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 95 mmHg after standardized treatment)
* There is a history of stroke, coronary artery disease, or vascular disease;
* Pregnant;
* Intestinal preparation cannot be carried out.
Source: ClinicalTrials.gov (NCT07073430). StuddyBuddy aggregates publicly available trial information.