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Recruiting NCT06981767

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

Conditions: Oral Lichen Planus

Sex: All
Healthy volunteers: No
Phase: PHASE2
Enrollment: 42
Sponsor: Cairo University

Location: Cairo University Cairo Cairo Governorate

Summary

Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.

Eligibility Criteria

Inclusion Criteria: * Patients suffering from symptomatic OLP * Patients free from any visible oral lesions other than OLP. * Patients who agreed to take the supplied interventions. * Patient who will agree to participate in the study. * Patients who will accept to sign the informed consent. Exclusion Criteria: * Patients suffering from any systemic disease. * Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks. * Treatment with any oral topical medications for at least four weeks prior to the study. * Pregnant and lactating mothers.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06981767). StuddyBuddy aggregates publicly available trial information.