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NCT06981767
Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus
Conditions: Oral Lichen Planus
Sex: All
Healthy volunteers: No
Phase: PHASE2
Enrollment: 42
Sponsor: Cairo University
Location: Cairo University Cairo Cairo Governorate
Summary
Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.
Eligibility Criteria
Inclusion Criteria:
* Patients suffering from symptomatic OLP
* Patients free from any visible oral lesions other than OLP.
* Patients who agreed to take the supplied interventions.
* Patient who will agree to participate in the study.
* Patients who will accept to sign the informed consent.
Exclusion Criteria:
* Patients suffering from any systemic disease.
* Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks.
* Treatment with any oral topical medications for at least four weeks prior to the study.
* Pregnant and lactating mothers.
Source: ClinicalTrials.gov (NCT06981767). StuddyBuddy aggregates publicly available trial information.