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Recruiting NCT06974838

Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability

Conditions: Autism Spectrum Disorder, Minimally Verbal Ability, Intellectual Disability

Sex: All
Ages: 8 Years – 30 Years
Healthy volunteers: No
Phase: NA
Enrollment: 60
Sponsor: Chang Gung Memorial Hospital

Location: Chang Gung Memorial Hospital Taoyuan

Summary

The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability

Eligibility Criteria

Inclusion Criteria: * Diagnosis of autism spectrum disorder, confirmed by DSM-5. * Individuals with minimal verbal ability or intellectual disability (FSIQ \< 70). Exclusion Criteria: * Current or past severe neurological disorders, such as epilepsy, or significant visual or hearing impairments. * Current or past severe systemic diseases, such as cardiovascular disease, diabetes, or multiple sclerosis. * History of severe brain injury. * Presence of implanted metal devices, such as a pacemaker or medication pump. * Current or past severe psychiatric disorders, such as schizophrenia, bipolar disorder, or major depressive disorder. * Pregnancy. * Significant brain abnormalities, such as intracranial space-occupying lesions. * Family history of epilepsy. * History of febrile seizures. * Concurrent use of medications that increase the risk of seizures. * Sleep disorders during rTMS procedures. * Skin lesions or trauma at the stimulation site. * Deemed ineligible by the principal investigator (PI). * Participation in another clinical trial within the past month. * Suicidal ideation or suicide attempts within the past year.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06974838). StuddyBuddy aggregates publicly available trial information.