Pulp Inflammatory Markers and Outcome of Pulpotomy

This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious pulp exposure. Pulp blood samples from the teeth will be collected during treatment, MMP9 levels will be recorded using Elisa kits. The teeth will be restored and followed up at 1 week, 6 months, 1, and 2 years. The teeth will be assesses both clinically and radiographically. The procedure will be success if the tooth is asymptomatic clinically and with normal periapical findings. The relationship between MMP9 level and success of treatment will be investigated.

Inclusion Criteria: * Non -contributory medical history (ASA 1) * Molar tooth with deep caries extending\>= 2/3 of dentine or exposing the pulp on the radiograph * The tooth should give positive response to cold sensibility testing * Clinical diagnosis of either reversible or irreversible pulpitis based on the symptoms and results of cold testing. * The tooth is restorable, probing pocket depth and mobility are within normal limits Exclusion Criteria: * Non-restorable tooth. * Signs of pulpal necrosis including sinus tract or swelling. * No enough bleeding after the pulpotomy procedure. * Inability to achieve hemostasis within 10 min after the pulpotomy.